Assistant Professor
Phone Numbers
Office
IRCB, Room 3040G
Educational History
Postdoctoral Fellow, Cardiovascular Medicine, Yale University, 2020
Ph.D., Bioengineering, University of Pennsylvania, 2015
B.Bm.E., Biomedical Engineering, University of Minnesota, 2009
Research Interests
Tissue Stiffness Homeostasis
Cellular and Molecular Mechanotransduction
Tissue Engineering and Regenerative Medicine
Awards, Honors, and Memberships
Maximizing Investigators' Research Award (MIRA), NIH (2024)
Ruth L. Kirschstein National Research Service Award (NRSA), NIH (2016)
Publications
Joshi, S., Naha, A., Ene, J., Holmes, C., *Li, Y., & *Driscoll, T. P. (2025). Cellular Uptake of Nanoparticles is Regulated by Integrin-Based Adhesion to the Extracellular Matrix. ACS Applied Materials and Interfaces, 18(2), 3515-3526. (*Corresponding author).
McDaniel, G., Li, Y., & *Driscoll, T. P. (2025). miR29a Loaded Extracellular Vesicles Derived from Human Mesenchymal Stem Cells Inhibit Fibrotic and Inflammatory Signaling. ACS Biomaterials Science and Engineering, 24.
Villalobos, C., Sadeghifar, A., Maggiorani, J., McDaniel, G., & *Driscoll, T. P. (2025). Actin Branching Regulates Cell Spreading and Force on Talin, but not Activation of YAP.
Naha, A., Sorensen, J., Lazarte, S., Joshi, S., & *Driscoll, T. P. (2025). Fibronectin Peptide Modified Hydrogels Activate a Contractile Phenotype in Nucleus Pulposus Cells. Advanced Biology, e00315, 10.
Naha, A., & *Driscoll, T. P. (2024). Fibronectin Sensitizes Activation of Contractility, YAP, and NF-κB in Intervertebral Disc Cells. Journal of Orthopedic Research, 42(2), 434-442.
*Driscoll, T. P., *Bidone, T. C., Ahn, S. J., Yu, A., Groisman, A., Voth, G. A., & Schwartz, M. A. (2021). Integrin-Based Mechanosensing is Mediated by Conformational Deformation. Biophysical Journal, 8.
*Driscoll, T. P., *Bidone, T. C., Ahn, S. J., Yu, A., Groisman, A., Voth, G. A., & Schwartz, M. A. (2021). Integrin-Based Mechanosensing is Mediated by Conformational Deformation. Biophysical Journal, 8.
Moro A#, Driscoll, T. P.#, Boraas LC, Armero W, Kasper DM, Baeyens N, Jouy C, Mallikarjun V, Swift J, Ahn SJ, Lee D, Zhang J, Gu M, Gerstein M, Schwartz MA, Nicoli S. microRNA-Dependent Regulation of Biomechanical Genes Establishes Tissue Stiffness Homeostasis. Nature Cell Biology, 2019 Mar; (#Co-first authors).
Heo, Su-Jin, Driscoll, T. P., Nerurkar, N. L., Baker, B. M., Chen, C. C., Lee, D. A., & Mauck, R. L. (2016). Differentiation alters stem cell nuclear architecture, mechanics, and mechano-sensitivity. eLife, 5, e18207.
Cosgrove, B. D., Mui, K. L., Driscoll, T. P., Caliari, S. R., Mehta, K. D., Assoian, R. K., Burdick, J. A., & Mauck, R. L. (2016). N-cadherin adhesive interactions modulate matrix mechanosensing and fate commitment of mesenchymal stem cells. Nature Materials, 15, 1297-1306.