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Jingjiao Guan, Ph.D.

Jingjiao Guan
Associate Professor
Phone Number(s)
Room Number
B337
Education
  • Ph.D., Biomedical Engineering, The Ohio State University, 2005
  • M.S., Biophysics, The Ohio State University, 2003
  • M.E., Materials Physics, University of Science and Technology, Beijing, China, 1998
  • B.E., Metal Physics, University of Science and Technology, Beijing, China, 1995
Research Interests
  • Micro/nano-devices for biosensing and drug delivery
Professional Affiliations & Qualifications
  • Postdoctoral Associate, National Science Foundation (NSF) Nanoscale Science and Engineering Center for Affordable Nanoengineering of Polymeric Biomedical Devices, The Ohio State University
Professional Memberships
  • Biomedical Engineering Society (BMES)
  • American Institute of Chemical Engineers (AIChE)
  • Materials Research Society (MRS)
Awards
  • New Investigator Award from the James and Esther King Biomedical Program of the Florida Department of Health, 2010
  • Outstanding Postdoctoral Student Majoring in Chemical Engineering, The American Institute of Chemists Foundation, 2008
Publications

Peer-reviewed Journal Articles: (* indicates corresponding author)

  1. Junfei Xia, Zhibin Wang, Yuanwei Yan, Zhijian Cheng, Li Sun, Yan Li, Yi Ren, and Jingjiao Guan*. Catalase-Laden Microdevices for Cell-Mediated Enzyme DeliveryLangmuir(2016) 32: 13386-13393.
  2. Yuanwei Yan, Julie Bejoy, Junfei Xia, Jingjiao Guan, Yi Zhou, Yan Li, Neural patterning of human induced pluripotent stem cells in 3-D cultures for studying biomolecule-directed differential cellular responsesActa Biomaterialia (2016) 42: 114-126.
  3. Junfei Xia, Zhibin Wang, Danting Huang, Yuanwei Yan, Yan Li, Jingjiao Guan*. Asymmetric biodegradable microdevices for cell-borne drug deliveryACS Applied Materials Interfaces (2015) 7(11): 6293-6299.
  4. Peipei Zhang, Yong Qiao, Junfei Xia, Jingjiao Guan, Liyuan Ma, Ming Su. Enhanced radiation therapy with multilayer microdisks containing radiosensitizing gold nanoparticlesACS Applied Materials Interfaces (2015) 7(8): 4518-4524.
  5. Zhibin Wang, Junfei Xia, Yuanwei Yan, Ang-Chen Tsai, Yan Li, Teng Ma, Jingjiao Guan*. Facile functionalization and assembly of live cells with microcontact-printed polymeric biomaterialsACS Applied Materials Interfaces (2015) 11: 80-87.
  6. Junfei Xia, Zhibin Wang, Danting Huang, Peipei Zhang, Brett Kirkland, Jingjiao Guan*.Self-referenced detection of Cu2+ using a crossbar array of protein-stabilized gold nanocluster and a thermoplasticScience Letters Journal (2015) 4: 196.
  7. Zhibin Wang, Junfei Xia, Sida Luo, Peipei Zhang, Zhiwei Xiao, Tao Liu, Jingjiao Guan*, Versatile surface micropatterning and functionalization enabled by microcontact printing of poly(4-aminostyrene)Langmuir (2014) 30: 13483-13490.
  8. Waris Obitayo, Sida Luo, Zhiwei Xiao, Tao Liu*, Jingjiao Guan*, Gel electrophoresis and Raman mapping for determining the length distribution of SWCNTsRSC Advances(2014) 4: 37070-37078.
  9. Peipei Zhang, Junfei Xia, Zhibin Wang, Jingjiao Guan*, Gold nanoparticles-packed microdisks for multiplex Raman labelling of cellsNanoscale (2014) 6: 8762-8768.
  10. Zhibin Wang, Junfei Xia, Jingjiao Guan*, Micro/nanocontact printing of water-soluble biomacromolecules and polymersScience Letters Journal (2014) 3: 58.
  11. Troy W. Lowry, Aubrey Kusi-Appiah, Jingjiao Guan, David van Winkle, Michael Davidson, Steven Lenhert, Materials Integration by NanointaglioAdvanced Materials Interfaces(2014) 1: 1300127.
  12. Zhibin Wang, Jingfang Wang, Zhiwei Xiao, Junfei Xia, Peipei Zhang, Tao Liu, Jingjiao Guan∗, A Paper Indicator for Triple-modality sensing of nitrite based on colorimetric assay, Raman spectroscopy, and electron paramagnetic resonance spectroscopyAnalyst (2013) 138: 7303-7307.
  13. Danting Huang, Zhibin Wang, Junfei Xia, Peipei Zhang, Brett Kirkland, Anant Paravastu*, Jingjiao Guan*, Microcontact printing of Alzheimer’s β-amyloid monomers and fibrilsEuropean Polymer Journal, 2013, 49 (10): 3052-3059.
  14. Brett Kirkland, Zhibin Wang, Peipei Zhang, Shin-ichiro Takebayashi, Steven Lenhert, David M. Gilbert, Jingjiao Guan∗, Low-cost fabrication of centimetre-scale periodic arrays of single plasmid DNA moleculesLab on a Chip, (2013) 13: 3367-3372.
  15. Yingru Liu, Brett Kirkland, James Shirley, Zhibin Wang, Peipei Zhang, Jacquelyn Stembridge, Wilson Wong, Shin-ichiro Takebayashi, David M. Gilbert, Steven Lenhert, Jingjiao Guan*, Development of single-cell array for large-scale DNA fluorescence in situ hybridizationLab on a Chip (2013) 13: 1316-1324.
  16. Peipei Zhang, Yingru Liu, Junfei Xia, Zhibin Wang, Brett Kirkland, Jingjiao Guan*, Top-down fabrication of polyelectrolyte-thermoplastic hybrid microparticles for unidirectional drug delivery to single cellsAdvanced Healthcare Materials (2013) 2: 540-545.
  17. Zhibin Wang, Peipei Zhang, Brett Kirkland, Yingru Liu, Jingjiao Guan*, Microcontact printing of polyelectrolytes on PEG using an unmodified PDMS stamp for micropatterning nanoparticles, DNA, proteins and cellsSoft Matter (2012) 8: 7630-7637.
  18. Xiaozhu Wang, Shin-ichiro Takebayashi, Evans Bernardin, David M. Gilbert, Ravindran Chella, Jingjiao Guan*, Microfluidic extraction and stretching of chromosomal DNA from single cell nuclei for DNA fluorescence in situ hybridizationBiomedical Microdevices(2012) 14: 443-451.
  19. Peipei Zhang, Jingjiao Guan*, Fabrication of Multilayered Microparticles by Integrating Layer-by-Layer Assembly and MicroContact PrintingSmall (2011) 7: 2998–3004.
  20. Jingjiao Guan, Pouyan E. Boukany, Orin Hemminger, Nan-Rong Chiou, Weibin Zha, Megan Cavanaugh, L. James Lee, Large laterally ordered nanochannel arrays from DNA combing and imprintingAdvanced Materials (2010) 22: 3997–4001.
  21. Chung Hsun Lin, Jingjiao Guan, Shiu Wu Chau, Shia Chung Chen, L. James Lee, Patterning nanowire and micro-/nanoparticle array on micropillar-structured surface: Experiment and modelingBiomicrofluidics (2010) 4: 034103-1-14.
  22. Chee Guan Koh, Xulang Zhang, Shujun Liu, Sharon Golan, Bo Yu, Xiaojuan Yang, Jingjiao Guan, Yan Jin, Yeshayahu Talmon, Natarajan Muthusamy, Kenneth K Chan, John C. Byrd, Robert J. Lee, Guido Marcucci, L. James Lee, Delivery of antisense oligodeoxyribonucleotide lipopolyplex nanoparticles assembled by microfluidic hydrodynamic focusingJournal of Controlled Release (2010) 141: 62-69.
  23. Chee Guan Koh, Xihai Kang, Yubing Xie, Zhengzheng Fei, Jingjiao Guan, Bo Yu, Xulang Zhang, L. James Lee, Delivery of polyethylenimine/DNA complexes assembled in a microfluidics deviceMolecular Pharmaceutics (2009) 6: 1333-1342.
  24. C H Lin, J Guan, S W Chau, L J Lee, Experimental and numerical analysis of DNA nanostrand array formation by molecular combing on microwell-patterned surfaceJournal of Physics D: Applied Physics (2009) 42: 025303.
  25. Xiaogang Pan, Jingjiao Guan, Jung-Woo Yoo, Arthur J. Epstein, L. James Lee, Robert J. Lee, Cationic lipid-coated magnetic nanoparticles associated with transferrin for gene deliveryInternational Journal of Pharmaceutics, (2008) 358: 263-270.
  26. Prashant Pradhan, Jingjiao Guan, Dongning Lu, Peng George Wang, L. James Lee, Robert J. Lee*, A Facile microfluidic method for production of liposomesAnticancer Research, (2008) 28: 943-948. Co-first author.
  27. Shengnian Wang, Jingjiao Guan, L. James Lee, Flow-guided assembly processesChemPhysChem, (2008) 9:967-973.
  28. Jingjiao Guan, Nicholas Ferrell, Bo Yu, Derek J. Hansford, L. James Lee, Simultaneous generation of hybrid arrays of micro/nanoparticles and nanowires by dewetting on micropillarsSoft Matter (2007) 2: 1369-1371. Cover article.
  29. Nan-Rong Chiou, Chunmeng Lu, Jingjiao Guan, L. James Lee, Arthur J. Epstein, Growth and alignment of polyaniline nanofibres with superhydrophobic, superhydrophilic and other propertiesNature Nanotechnology (2007) 2: 354-357.
  30. Jingjiao Guan, Bo Yu, L. James Lee, Forming highly ordered arrays of functionalized polymer nanowires by dewetting on micropillarsAdvanced Materials (2007) 19: 1212-1217.
  31. Jingjiao Guan, Hongyan He, Derek Hansford, L. James Lee, Fabrication of particulate reservoir-containing, capsule-like, and self-foldable polymer microstructures for drug deliverySmall (2007) 3: 412-418.
  32. Hongyan He, Jingjiao Guan, L. James Lee, An oral delivery device based on self-folding hydrogelsJournal of Controlled Release (2006) 110: 339-346.
  33. Jingjiao Guan, Nick Ferrell, L. James Lee, Derek Hansford, Fabrication of polymeric microparticles for drug delivery by soft LithographyBiomaterials (2006) 27: 4034-4041.
  34. Jingjiao Guan, L. James Lee, Generating highly ordered DNA nanostrand arrayProceedings of National Academy of Science, U. S. A. (2005) 102: 18321-18325. Prominently featured on the cover and in a "This Week in PNAS" introductory article. Reported on science news websites worldwide.
  35. Jingjiao Guan, Hongyan He, L. James Lee, Derek J. Hansford, Self-Folding of hydrogel three dimensional microstructuresJournal of Physical Chemistry B (2005) 109: 23134-23137.
  36. Jingjiao Guan, Aravind Chakrapani, Derek J. Hansford, Polymer microparticles fabricated by soft lithographyChemistry of Materials (2005) 17: 6227-6229.
  37. Yi-Je Juang, Xin Hu, Shengnian Wang, L. James Lee, Chunmeng Lu, Jingjiao Guan, Electrokinetic interactions in microscale cross-slot flowApplied Physics Letters (2005) 87: 244105-1-3.
  38. Junwei Li, Chen Wang, Guangyi Shang, Qingmin Xu, Zhang Lin, Jingjiao Guan, Chunli Bai, Friction coefficients derived from apparent height variations in contact mode atomic force microscopy imagesLangmuir (1999) 15: 7662-7669.
  39. Jingjiao Guan, Chen Wang, Wuyang Chu, Atomic structure of loaded crack tip by AFMScripta Materialia (1998) 39: 1211-1214.
  40. Ming Su, Chunli Bai, Chen Wang, Jingjiao Guan, Substrate-dependent dispersion behavior of polymer-protected Pt colloid studied by SPMApplied Surface Science (1998) 133: 23 -26.
  41. Mingzhang Wang, Shi Lin, Jinxu Li, Jingjiao Guan, Jimei Xiao, Fatigue damage and crack initiation in [112] aluminum single CrystalJinshu Xuebao (1997) 33: 1015.
Book Chapters
  1. Jingjiao Guan, Chapter: Microcontact printing, Book: The Nanobiotechnology Handbook, Publisher: CRC Press, ISBN-10: 1439838690, Editor: Yubing Xie, 2012.
  2. Jingjiao Guan, L. James Lee, Chapter: Guided Assembly by Surface Controlled Dewetting and Evaporation, Book: Evaporative Self-Assembly of Ordered Complex Structures, Publisher: World Scientific Publishing Company, Singapore. To be published.
  3. Jingjiao Guan, Xiaogang Pan, L. James Lee, Robert J. Lee, Chapter: Viral, Non-Viral and Physical Methods for Gene Delivery, Book: Biopharmaceutical Drug Design and Development, Publisher: Humana Press, (2008) 141-174.
  4. Jingjiao Guan, Hongyan He, Bo Yu, L. James Lee, Chapter: Polymeric Nanostructures for Controlled Drug and Gene Delivery, Book: Biomedical Nanostructures, Publisher: John Wiley & Sons, (2008) 115-137.